Congress abstract
Marks L, Weber A, Rittenhouse H, Macairan ML, Yee S, Bostwick D. Presented at the 2010 annual meeting of the American Urological Association (AUA). May 29-June 3, 2010. San Francisco, CA. Abstract 805
- This small study in 10 men with prostatitis shows that contrary to serum prostate specific antigen (PSA) levels, the Prostate CAncer gene 3 (PCA3) Score is not affected by prostatitis
- This study included 10 men with a clinical diagnosis of prostatitis and increased PSA levels (median 11 ng/mL) at diagnosis
- The median PSA level decreased from 11 ng/mL at diagnosis to 2.0 ng/mL one year after antibiotic treatment. PSA levels remained increased for months after treatment
- The median %free PSA level increased from 12 at diagnosis to 21 at 6-12 months
- The median PCA3 Score at diagnosis was normal (11.8) and unaffected by prostatitis
- It was concluded that the preliminary data from this small study suggest that the apparent prostate cancer-specificity of the PCA3 Score is maintained during prostatitis while in contrast PSA levels are elevated. In case of elevated PSA levels due to prostatitis, the PCA3 test could aid in the decision whether or not a prostate biopsy is necessary