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Congress abstract

Biological variation of PCA3 Score in men previously diagnosed with prostate cancer

Partin AW, Mangold LA, Gurganus RT, Blase A, Groskopf J, Deras IL, Mathis J, Carter HB, Rittenhouse H.
J Urol 2007;177(4):538 (abs. 1623)

This abstract was presented as a poster at the 2007 Annual Meeting of the American Urological Association (AUA), 19-24 May, Anaheim, USA.
A total of 29 PCa patients awaiting treatment or managed with watchful waiting provided a urine sample once a week for 4 weeks and the PCA3 Scores were measured.
The variation in the individual subject’s PCA3 Score at the 4 visits was small.
Moreover, this was independent of the applied DRE method (routine diagnostic DRE or a 3-strokes per lobe DRE) (Figure left).
The informative rate (urine samples with sufficient mRNA to calculate the PCA3 Score) was also comparable for both DRE methods (Figure right).