The PCA3 Score is independent of prostate gland volume, and can synergize with other patient information for predicting biopsy outcome

Groskopf J, Blase A, Deras IL, Koo S, Aubin SMJ, Marks LS, Rittenhouse H, Fradet Y.
Eur Urol Suppl 2007;6(2):48 (abs. 102)

• This abstract was presented as a poster at the 22nd European Association of Urology (EAU) congress, 21-24 March 2007, Berlin, Germany.
• It shows in 570 men scheduled for biopsy that the performance of the PCA3 Assay is equivalent in men undergoing first/initial biopsy (1st Bx) compared to those undergoing repeat biopsy after previous negative biopsy(ies).
• This is confirmed by overlapping ROC (receiver-operating characteristics) curves and comparable sensitivity and specificity (Figure).

Reviewed by

Prof. J. Schalken, Prof. B. Tombal, Prof. H. Van Poppel

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