Prostate CAncer gene 3 (PCA3) is a new gene-based test

Prostate CAncer gene 3 (PCA3) is a gene-based test carried out on a urine sample.

If you are concerned about prostate cancer because of an elevated PSA or are feeling insecure about a previously performed (negative) biopsy, the PCA3 urine test can provide additional information that may help you and your physician to decide whether a (new) biopsy is really needed.

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PCA3 Patient brochure

  • When can the PCA3 test help?
  • How is the PCA3 test performed?
  • Understanding your PCA3 Score

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Editorial board

Prof. Bertrand TombalBrussel, Belgium
Prof. Hendrik Van PoppelLeuven, Belgium
Prof. Jack SchalkenNijmegen, Netherlands
Mr. Mark SpeakmanTaunton, United Kingdom

Questions and Answers

PCA3 (Prostate CAncer gene 3) is a gene which is prostate cancer specific. Unlike prostate specific antigen (PSA), PCA3 is only produced by PCa cells and not affected by prostate size. It discriminates better than PSA between PCa and benign...
Prof. Jack Schalken
Prof. Bertrand ...
Prof. Hendrik V...
The major difference between PCA3 (Prostate CAncer gene 3) and prostate specific antigen (PSA) is the fact that PCA3 is prostate cancer (PCa)-specific and PSA is not. This is due to the fact that PSA is also produced by non-cancerous prosta...
Prof. Jack Schalken
Prof. Bertrand ...
Prof. Hendrik V...
The result of the PCA3 (Prostate CAncer gene 3) test, the PCA3 Score, indicates the likelihood that you will have prostate cancer (PCa) diagnosed after examining under a microscope prostate tissue samples obtained during a prostate biopsy....
Prof. Jack Schalken
Prof. Bertrand ...
Prof. Hendrik V...
The PCA3 (Prostate CAncer gene 3) test is not a replacement for prostate specific antigen (PSA). It is an additional tool to more accurately predict prostate biopsy outcome. It is helpful for deciding if biopsy is really needed in men suspe...
Prof. Jack Schalken
Prof. Bertrand ...
Prof. Hendrik V...
The PCA3 test provides additional information which can help you and your doctor decide if a biopsy is needed or can be delayed (see also PCA3 background information). Other factors such as your age, prostate size, prostate specific antigen...
Prof. Hendrik V...

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